Antisense Oligonucleotide-Induced Amyloid Precursor Protein Splicing Modulation as a Therapeutic Approach for Dutch-Type Cerebral Amyloid Angiopathy-Reference-Cited by-同舟云学术

Antisense Oligonucleotide-Induced Amyloid Precursor Protein Splicing Modulation as a Therapeutic Approach for Dutch-Type Cerebral Amyloid Angiopathy

Published:2021-10-01 Issue:5 Volume:31 Page:351-363
ISSN:2159-3337
Container-title:Nucleic Acid Therapeutics
language:en
Short-container-title:Nucleic Acid Therapeutics

Author:

Daoutsali Elena¹^ORCID,Hailu Tsinatkeab T.²,Buijsen Ronald A.M.¹^ORCID,Pepers Barry A.¹,van der Graaf Linda M.¹,Verbeek Marcel M.³,Curtis Daniel²⁴,de Vlaam Thomas²,van Roon-Mom Willeke M.C.¹

Affiliation:

1. Department of Human Genetics, Leiden University Medical Center, Leiden, the Netherlands.

2. Amylon Therapeutics, Leiden, the Netherlands.

3. Departments of Neurology and Laboratory Medicine, Radboud Alzheimer Centre, Radboud University Medical Center, Donders Institute for Brain, Cognition and Behaviour, Nijmegen, the Netherlands.

4. Atalanta Therapeutics, Boston, Massachusetts, USA.

Publisher

Mary Ann Liebert Inc

Subject

Drug Discovery,Genetics,Molecular Biology,Molecular Medicine,Biochemistry

Link

https://www.liebertpub.com/doi/pdf/10.1089/nat.2021.0005

Reference37 articles.

1. Hereditary Cerebral Hemorrhage with Amyloidosis-Dutch Type (HCHWA-D): I - A Review of Clinical, Radiologic and Genetic Aspects

2. Amyloid β in hereditary cerebral hemorrhage with amyloidosis-Dutch type

3. A Western Australian kindred with Dutch cerebral amyloid angiopathy

4. Dutch hereditary cerebral amyloid angiopathy: Structural lesions and apolipoprotein E genotype

5. Expression and cellular localization of amyloid β-protein precursor transcripts in normal human brain and in Alzheimer's disease

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