Disruption of macrophage pro-inflammatory cytokine release in Crohn's disease is associated with reduced optineurin expression in a subset of patients
Author:
Affiliation:
1. Microbial Diseases; Eastman Dental Institute; University College London; London UK
2. Division of Medicine; University College London; London UK
3. Department of Gastroenterology; UCLH NHS Foundation Trust; London UK
Funder
Wellcome Trust
Publisher
Wiley
Subject
Immunology,Immunology and Allergy
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1111/imm.12338/fullpdf
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2. Genetics in twins with Crohn's disease: less pronounced than previously believed?;Halfvarson;Inflamm Bowel Dis,2011
3. Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease;Barrett;Nat Genet,2008
4. Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease;Jostins;Nature,2012
5. Evidence from genetics for a role of autophagy and innate immunity in IBD pathogenesis;Parkes;Dig Dis,2012
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