Rice endosperm is cost-effective for the production of recombinant griffithsin with potent activity against HIV

Author:

Vamvaka Evangelia1ORCID,Arcalis Elsa2,Ramessar Koreen3,Evans Abbey4,O'Keefe Barry R.35,Shattock Robin J.4,Medina Vicente1,Stöger Eva2,Christou Paul16,Capell Teresa1

Affiliation:

1. Department of Plant Production and Forestry Science; School of Agrifood and Forestry Science and Engineering (ETSEA); University of Lleida-Agrotecnio Center; Lleida Spain

2. Department for Applied Genetics and Cell Biology; Molecular Plant Physiology and Crop Biotechnology; University of Natural Resources and Life Sciences; Vienna Austria

3. Molecular Targets Laboratory; Center for Cancer Research; National Cancer Institute; NIH; Frederick MD USA

4. Department of Medicine; Imperial College London, Norfolk Place; London UK

5. Natural Products Branch; Developmental Therapeutics Program; Division of Cancer Treatment and Diagnosis; National Cancer Institute, NIH; Frederick MD USA

6. Catalan Institute for Research and Advanced Studies (ICREA); Barcelona Spain

Funder

Ministerio de Ciencia e Innovación

COST Action

National Cancer Institute

National Institutes of Health

Center for Cancer Research

Publisher

Wiley

Subject

Plant Science,Agronomy and Crop Science,Biotechnology

Reference71 articles.

1. Overview of microbicides for the prevention of human immunodeficiency virus;Abdool Karim;Best Pract. Res. Clin. Obstet. Gynaecol.,2012

2. Mannose-rich glycosylation patterns on HIV-1 subtype C gp120 and sensitivity to the lectins, Griffithsin, Cyanovirin-N and Scytovirin;Alexandre;Virology,2010

3. Expression of a functional recombinant human basic fibroblast growth factor from transgenic rice seeds;An;Int. J. Mol. Sci.,2013

4. Unexpected deposition patterns of recombinant proteins in post-endoplasmic reticulum compartments of wheat endosperm;Arcalis;Plant Physiol.,2004

5. Polyclonal antibodies for the specific detection of tobacco host cell proteins can be generated more efficiently following RuBisCO depletion and the removal of endotoxins;Arfi;Biochem. J.,2015

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