NLRP4 negatively regulates type I interferon response and influences the outcome in anti‐programmed cell death protein (PD)‐1/PD‐ligand 1 therapy

Author:

Wang Hui1,Xia Liliang12,Yao Cheng‐cheng2,Dong Hui3,Yang Yi1,Li Chong4,Ji Wen‐xiang1,Sun Rui‐ming2,Duan Huang‐qi5,Mengzhou Wenli1,Xia Wei‐min5,Wang Shu‐jun2,Ji Ping2,Li Ziming1,Jiao Lei6,Wang Ying278,Lu Shun1ORCID

Affiliation:

1. Department of Shanghai Lung Cancer Center Shanghai Chest Hospital Shanghai Jiao Tong University Shanghai China

2. Department of Immunology and Microbiology Shanghai Institute of Immunology Shanghai Jiao Tong University School of Medicine Shanghai China

3. Department of Gastroenterology Shanghai Key Laboratory of Pancreatic Diseases Shanghai General Hospital Affiliated to Shanghai Jiao Tong University School of Medicine Shanghai China

4. Department of Oncology Shanghai Medical College Cancer Institute Fudan University Shanghai Cancer Center Fudan University Shanghai China

5. Department of Urology Xinhua Hospital affiliated to Shanghai Jiao Tong University School of Medicine Shanghai China

6. Department of High Content Pathology Center Panovue Biological Technology Co., Ltd Beijing China

7. Shanghai‐MOST Key Laboratory of Health and Disease Genomics Chinese National Human Genome Center at Shanghai Shanghai China

8. Key Laboratory of Cell Differentiation and Apoptosis of Chinese Ministry of Education Shanghai Jiao Tong University School of Medicine Shanghai China

Funder

National Natural Science Foundation of China

Publisher

Wiley

Subject

Cancer Research,Oncology,General Medicine

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