Mucosal IL13RA2 expression predicts nonresponse to anti-TNF therapy in Crohn's disease-Reference-Cited by-同舟云学术

Mucosal IL13RA2 expression predicts nonresponse to anti-TNF therapy in Crohn's disease

Published:2019-01-20 Issue:5 Volume:49 Page:572-581
ISSN:0269-2813
Container-title:Alimentary Pharmacology & Therapeutics
language:en
Short-container-title:Aliment Pharmacol Ther

Author:

Verstockt Bram¹²^ORCID,Verstockt Sare³,Creyns Brecht⁴,Tops Sophie⁵,Van Assche Gert¹²,Gils Ann⁵,Ceuppens Jan L.⁴,Vermeire Séverine¹²,Ferrante Marc¹²^ORCID,Breynaert Christine⁴

Affiliation:

1. Department of Chronic Diseases, Metabolism and Ageing; Translational Research Center for Gastrointestinal Disorders (TARGID), KU Leuven; Leuven Belgium

2. Department of Gastroenterology and Hepatology; University Hospitals Leuven, KU Leuven; Leuven Belgium

3. Department of Human Genetics; Laboratory for Complex Genetics; KU Leuven; Leuven Belgium

4. Department of Microbiology and Immunology; Laboratory of Clinical Immunology, KU Leuven; Leuven Belgium

5. Department of Pharmaceutical and Pharmacological Sciences; Laboratory for Therapeutic and Diagnostic Antibodies, KU Leuven; Leuven Belgium

Funder

Clinical Research Fund KOF

H2020 European Research Council

Publisher

Wiley

Subject

Pharmacology (medical),Gastroenterology,Hepatology

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1111/apt.15126/fullpdf

Reference40 articles.

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2. Inflammatory bowel disease: towards a personalized medicine;Flamant;Therap Adv Gastroenterol,2018

3. Mucosal gene signatures to predict response to infliximab in patients with ulcerative colitis;Arijs;Gut,2009

4. Predictive value of epithelial gene expression profiles for response to infliximab in Crohn's disease;Arijs;Inflamm Bowel Dis,2010

5. Effects of epithelial IL-13RA2 expression in inflammatory bowel diseases;Verstockt;Front Immunol,2018

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