Author:
Babayeva Gulustan H.,Ibrahimli Hikmet I.,Guliyev Ferid V.,Asadova Gunay V.,Mahmudov Umud R.,Hasanov Rafail H.,Kh. Verdiyev Emin,Musayev Jamal S.,Hasanova Aychin I.,Hasanov Rashad A.,Afandiyeva Nargiz E.,Isgandarov Namig O.,Maharramova Tunzala A.
Abstract
Eosinophils, one of the subgroups of leukocytes, are present in the gastrointestinal tract, with the exception of the esophagus (their presence in quantities of 15 or more is considered eosinophilic esophagitis). Much of the research on eosinophils has focused on their responses against helminths and type II immune system disorders. However, information on the role of eosinophils in the development and maintenance of inflammatory processes, as well as in the formation and progression of fibrotic changes in patients with inflammatory bowel diseases is limited. With increasing interest in innate immunity and the fact that eosinophil granules contain certain inflammatory mediators, eosinophils are becoming one of the current objects of study in inflammatory bowel diseases. In this paper, the authors presented already known data on the functions of eosinophils in inflammatory bowel diseases and some other chronic inflammatory conditions, and also presented the results of their own research on the role and influence of eosinophils on the course of inflammatory bowel diseases.