Activation of σ1 and σ2 receptors by afobazole increases glial cell survival and prevents glial cell activation and nitrosative stress after ischemic stroke-Reference-Cited by-同舟云学术

Activation of σ1 and σ2 receptors by afobazole increases glial cell survival and prevents glial cell activation and nitrosative stress after ischemic stroke

Published:2016-09-01 Issue:3 Volume:139 Page:497-509
ISSN:0022-3042
Container-title:Journal of Neurochemistry
language:en
Short-container-title:J. Neurochem.

Author:

Katnik Christopher¹,Garcia Angela¹,Behensky Adam A.¹,Yasny Ilya E.²,Shuster Alex M.³,Seredenin Sergei B.⁴,Petrov Andrey V.²,Cuevas Javier¹

Affiliation:

1. Department of Molecular Pharmacology and Physiology; Morsani College of Medicine; University of South Florida; Tampa Florida USA

2. Inbio Ventures; Moscow Russia

3. IBC Generium; Moscow Russia

4. Zakusov Institute of Pharmacology; Moscow Russia

Funder

IBC Generium

Publisher

Wiley

Subject

Cellular and Molecular Neuroscience,Biochemistry

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1111/jnc.13756/fullpdf

Reference43 articles.

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2. Sigma-1 receptor ligand PRE-084 reduced infarct volume, neurological deficits, pro-inflammatory cytokines and enhanced anti-inflammatory cytokines after embolic stroke in rats;Allahtavakoli;Brain Res. Bull.,2011

3. Immunocytochemical localization of the sigma(1) receptor in the adult rat central nervous system;Alonso;Neuroscience,2000

4. Afobazole activation of sigma-1 receptors modulates neuronal responses to amyloid-beta25-35;Behensky;J. Pharmacol. Exp. Ther.,2013a

5. Stimulation of sigma receptors with afobazole blocks activation of microglia and reduces toxicity caused by amyloid-beta25-35;Behensky;J. Pharmacol. Exp. Ther.,2013b

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