Discovery of WLB-89462, a New Drug-like and Highly Selective σ2 Receptor Ligand with Neuroprotective Properties
Author:
Affiliation:
1. Welab Barcelona, Parc Científic Barcelona, C/Baldiri Reixac 4-8,08028 Barcelona, Spain
Publisher
American Chemical Society (ACS)
Subject
Drug Discovery,Molecular Medicine
Link
https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.3c01060
Reference72 articles.
1. A proposal for the classification of sigma binding sites
2. Sigma receptors: recent advances and new clinical potentials
3. The sigma-1 receptor chaperone as an inter-organelle signaling modulator
4. Purification, molecular cloning, and expression of the mammalian sigma1-binding site.
Cited by 2 articles. 订阅此论文施引文献 订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献
1. WLB-87848, a Selective σ1 Receptor Agonist, with an Unusually Positioned NH Group as Positive Ionizable Moiety and Showing Neuroprotective Activity;Journal of Medicinal Chemistry;2024-05-16
2. Structure-Affinity relationships of novel σ2R/TMEM97 ligands;Bioorganic Chemistry;2024-04
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