Language and reading impairments are associated with increased prevalence of non‐right‐handedness-Reference-Cited by-同舟云学术

Language and reading impairments are associated with increased prevalence of non‐right‐handedness

Published:2023-02-13 Issue:4 Volume:94 Page:970-984
ISSN:0009-3920
Container-title:Child Development
language:en
Short-container-title:Child Development

Author:

Abbondanza Filippo¹^ORCID,Dale Philip S.²^ORCID,Wang Carol A.³,Hayiou‐Thomas Marianna E.⁴,Toseeb Umar⁵^ORCID,Koomar Tanner S.⁶,Wigg Karen G.⁷,Feng Yu⁷,Price Kaitlyn M.⁷⁸⁹,Kerr Elizabeth N.¹⁰¹¹,Guger Sharon L.¹¹,Lovett Maureen W.⁸¹⁰,Strug Lisa J.¹²¹³,van Bergen Elsje¹⁴^ORCID,Dolan Conor V.¹⁴,Tomblin J. Bruce⁶,Moll Kristina¹⁵,Schulte‐Körne Gerd¹⁵,Neuhoff Nina¹⁵,Warnke Andreas¹⁶,Fisher Simon E.¹⁷¹⁸,Barr Cathy L.⁷⁸⁹,Michaelson Jacob J.⁶,Boomsma Dorret I.¹⁴,Snowling Margaret J.¹⁹^ORCID,Hulme Charles²⁰^ORCID,Whitehouse Andrew J. O.²¹,Pennell Craig E.³,Newbury Dianne F.²²,Stein John²³,Talcott Joel B.²⁴,Bishop Dorothy V. M.¹⁹,Paracchini Silvia¹^ORCID

Affiliation:

1. School of Medicine University of St Andrews St Andrews UK

2. Department of Speech and Hearing Sciences University of New Mexico Albuquerque New Mexico USA

3. School of Medicine and Public Health University of Newcastle Callaghan New South Wales Australia

4. Department of Psychology University of York York UK

5. Department of Education University of York York UK

6. Department of Psychiatry The University of Iowa Iowa City Iowa USA

7. Division of Experimental and Translational Neuroscience, Krembil Research Institute University Health Network Toronto Ontario Canada

8. Program in Neuroscience and Mental Health Hospital for Sick Children Toronto Ontario Canada

9. Department of Physiology University of Toronto Toronto Ontario Canada

10. Department of Paediatrics University of Toronto Toronto Ontario Canada

11. Department of Psychology Hospital for Sick Children Toronto Ontario Canada

12. Genetics and Genome Biology Hospital for Sick Children Toronto Ontario Canada

13. Dalla Lana School of Public Health University of Toronto Toronto Ontario Canada

14. Department of Biological Psychology Vrije Universiteit Amsterdam Amsterdam The Netherlands

15. Department of Child and Adolescent Psychiatry, Psychotherapy and Psychosomatics Ludwig‐Maximilians‐University Hospital Munich Munchen Germany

16. Julius‐Maximilians‐University Würzburg Würzburg Germany

17. Language and Genetics Department Max Planck Institute for Psycholinguistics Nijmegen The Netherlands

18. Donders Institute for Brain, Cognition and Behaviour Radboud University Nijmegen The Netherlands

19. Department of Experimental Psychology University of Oxford Oxford UK

20. Department of Education University of Oxford Oxford UK

21. Telethon Kids Institute University of Western Australia Perth Western Australia Australia

22. Department of Biological and Medical Sciences Oxford Brookes University Oxford UK

23. Department of Physiology University of Oxford Oxford UK

24. Aston Brain Center, School of Life and Health Sciences Aston University Birmingham UK

Abstract

AbstractHandedness has been studied for association with language‐related disorders because of its link with language hemispheric dominance. No clear pattern has emerged, possibly because of small samples, publication bias, and heterogeneous criteria across studies. Non‐right‐handedness (NRH) frequency was assessed in N = 2503 cases with reading and/or language impairment and N = 4316 sex‐matched controls identified from 10 distinct cohorts (age range 6–19 years old; European ethnicity) using a priori set criteria. A meta‐analysis (Ncases = 1994) showed elevated NRH % in individuals with language/reading impairment compared with controls (OR = 1.21, CI = 1.06–1.39, p = .01). The association between reading/language impairments and NRH could result from shared pathways underlying brain lateralization, handedness, and cognitive functions.

Funder

H2020 European Research Council

National Health and Medical Research Council

Nederlandse Organisatie voor Wetenschappelijk Onderzoek

Royal Society

Wellcome Trust

University of Bristol

Max-Planck-Gesellschaft

Publisher

Wiley

Subject

Developmental and Educational Psychology,Education,Pediatrics, Perinatology and Child Health