Allosteric interactions at adenosine A1and A3receptors: new insights into the role of small molecules and receptor dimerization

Author:

Hill Stephen J1,May Lauren T2,Kellam Barrie3,Woolard Jeanette1

Affiliation:

1. Cell Signalling Research Group; School of Biomedical Sciences; Medical School; Queen's Medical Centre; University of Nottingham; Nottingham UK

2. Drug Discovery Biology; Monash Institute of Pharmaceutical Sciences & Department of Pharmacology; Monash University; Parkville Vic. Australia

3. School of Pharmacy; Centre for Biomolecular Sciences; University of Nottingham, University Park; Nottingham UK

Publisher

Wiley

Subject

Pharmacology

Reference115 articles.

1. Partial adenosine A1-receptor agonists for cardiovascular therapies;Albrecht-Kupper;Purinergic Signal,2012

2. The Concise Guide to PHARMACOLOGY 2013/14: G Protein-Coupled Receptors;Alexander;Br J Pharmacol,2013

3. Selective potentiation by an A1 adenosine receptor enhancer of the negative dromotropic action of adenosine in the guinea-pig heart;Amoah-Apraku;J Pharm Exp Ther,1993

4. 5-Substituted 2-aminothiophenes as A1 adenosine receptor allosteric enhancers;Aurelio;Bioorg Med Chem,2008

5. Allosteric modulators of the adenosine A1 receptor: synthesis and pharmacological evaluation of 4-substituted 2-amino-3-benzoylthiophenes;Aurelio;J Med Chem,2009

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