Detection of the secondary, low-affinity β1-adrenoceptor site in living cells using the fluorescent CGP 12177 derivative BODIPY-TMR-CGP
Author:
Affiliation:
1. Cell Signalling Research Group, School of Life Sciences; University of Nottingham; Nottingham UK
Funder
Medical Research Council
Publisher
Wiley
Subject
Pharmacology
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1111/bph.12858/fullpdf
Reference40 articles.
1. The concise guide to pharmacology 2013/14: G protein-coupled receptors;Alexander;Br J Pharmacol,2013
2. Site of action of beta-ligands at the human β1-adrenoceptor;Baker;J Pharmacol Exp Ther,2005
3. Pharmacological characterization of CGP 12177 at the human β2-adrenoceptor;Baker;Br J Pharmacol,2002
4. Agonist actions of ‘beta-blockers’ provide evidence for two agonist activation sites or conformations of the human β1-adrenoceptor;Baker;Mol Pharmacol,2003a
5. Pharmacology and direct visualisation of BODIPY-TMR-CGP: a long-acting fluorescent β2-adrenoceptor agonist;Baker;Br J Pharmacol,2003b
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