Development of novel fluorescent histamine H1-receptor antagonists to study ligand-binding kinetics in living cells-Reference-Cited by-同舟云学术

Development of novel fluorescent histamine H1-receptor antagonists to study ligand-binding kinetics in living cells

Published:2018-01-25 Issue:1 Volume:8 Page:
ISSN:2045-2322
Container-title:Scientific Reports
language:en
Short-container-title:Sci Rep

Author:

Stoddart Leigh A.,Vernall Andrea J.,Bouzo-Lorenzo Monica,Bosma Reggie,Kooistra Albert J.,de Graaf Chris^ORCID,Vischer Henry F.,Leurs Rob,Briddon Stephen J.,Kellam Barrie,Hill Stephen J.^ORCID

Publisher

Springer Science and Business Media LLC

Subject

Multidisciplinary

Link

http://www.nature.com/articles/s41598-018-19714-2.pdf

Reference65 articles.

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3. Waring, M. J. et al. An analysis of the attrition of drug candidates from four major pharmaceutical companies. Nat Rev Drug Discov 14, 475–486 (2015).

4. Kumari, P., Ghosh, E. & Shukla, A. K. Emerging Approaches to GPCR Ligand Screening for Drug Discovery. Trends Mol Med 21, 687–701 (2015).

5. Shonberg, J., Kling, R. C., Gmeiner, P. & Lober, S. GPCR crystal structures: Medicinal chemistry in the pocket. Bioorg Med Chem 23, 3880–3906 (2015).

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