Mechanisms underlying the cytotoxicity of a novel quinazolinedione-based redox modulator, QD232, in pancreatic cancer cells

Author:

Pathania Divya1,Kuang Yuting12,Sechi Mario3,Neamati Nouri12

Affiliation:

1. Department of Pharmacology and Pharmaceutical Sciences; School of Pharmacy; University of Southern California; Los Angeles CA USA

2. Department of Medicinal Chemistry; College of Pharmacy, and Translational Oncology Program; University of Michigan; Ann Arbor MI USA

3. Department of Chemistry and Pharmacy; University of Sassari; Sassari Italy

Publisher

Wiley

Subject

Pharmacology

Reference55 articles.

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3. Inhibition of focal adhesion kinase and src increases detachment and apoptosis in human neuroblastoma cell lines;Beierle;Mol Carcinog,2010

4. The dual kinase complex FAK-Src as a promising therapeutic target in cancer;Bolos;Onco Targets Ther,2010

5. Reciprocal regulation of c-Src and STAT3 in non-small cell lung cancer;Byers;Clin Cancer Res,2009

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