Author:
Kuribayashi Shunji,Uno Yasuhiro,Naito Shinsaku,Yamazaki Hiroshi
Subject
Pharmacology,Toxicology,General Medicine
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2. Species differences in hydrolase activities toward OT-7100 responsible for different bioavailability in rats, dogs, monkeys and humans;Kuribayashi;Xenobiotica,2006
3. Human cytochrome P450 1A2 involvement in the formation of reactive metabolites from a species-specific hepatotoxic pyrazolopyrimidine derivative, 5-n-butyl-7-(3,4,5-trimethoxybenzoylamino)pyrazolo[1,5-a]pyrimidine;Kuribayashi;Chem Res Toxicol,2009
4. Approach for in vivo protein bindings of 5-n-butyl-pyrazolo[1,5-a]pyrimidine bioactivated in chimeric mice with humanized liver by two-dimensional electrophoresis with accelerator mass spectrometry;Yamazaki;Chem Res Toxicol,2010
5. CYP1D1, pseudogenized in human, is expressed and encodes a functional drug-metabolizing enzyme in cynomolgus monkey;Uno;Biochem Pharmacol,2011
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