Therapeutic potential of novel Cell Division Cycle Kinase 7 inhibitors on TDP‐43‐related pathogenesis such as Frontotemporal Lobar Degeneration (FTLD) and amyotrophic lateral sclerosis (ALS)-Reference-Cited by-同舟云学术

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Therapeutic potential of novel Cell Division Cycle Kinase 7 inhibitors on TDP‐43‐related pathogenesis such as Frontotemporal Lobar Degeneration (FTLD) and amyotrophic lateral sclerosis (ALS)

Published:2020-07-17 Issue:3 Volume:156 Page:379-390
ISSN:0022-3042
Container-title:Journal of Neurochemistry
language:en
Short-container-title:J Neurochem

Author:

Vaca Gabriela¹,Martinez‐Gonzalez Loreto²,Fernandez Ana¹,Rojas‐Prats Elisa²,Porras Gracia¹,Cuevas Eva P.²,Gil Carmen²³,Martinez Ana²³^ORCID,Martin‐Requero Ángeles¹³^ORCID

Affiliation:

1. Department of Molecular Biomedicine Centro de Investigaciones Biológicas Margarita Salas (CSIC) Madrid Spain

2. Department of Structural and Chemical Biology Centro de Investigaciones Biológicas Margarita Salas (CSIC) Madrid Spain

3. Centro de Investigación Biomédica en Red de Enfermedades neurodegenerativas (CIBERNED) Instituto de Salud Carlos III Madrid Spain

Funder

Comunidad de Madrid

Instituto de Salud Carlos III

Secretaría de Educación Superior, Ciencia, Tecnología e Innovación

Ministerio de Educación de la Nación

Publisher

Wiley

Subject

Cellular and Molecular Neuroscience,Biochemistry

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1111/jnc.15118

Reference41 articles.

1. The El Escorial criteria: Strengths and weaknesses

2. Inactivation of CDK/pRb Pathway Normalizes Survival Pattern of Lymphoblasts Expressing the FTLD-Progranulin Mutation c.709-1G>A

3. Alteration in cell cycle-related proteins in lymphoblasts from carriers of the c.709-1G>A PGRN mutation associated with FTLD-TDP dementia

4. PGRN haploinsufficiency increased Wnt5a signaling in peripheral cells from frontotemporal lobar degeneration-progranulin mutation carriers

5. Targeting TDP-43 phosphorylation by Casein Kinase-1δ inhibitors: a novel strategy for the treatment of frontotemporal dementia

Cited by 21 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Aberrant protein aggregation in amyotrophic lateral sclerosis;Journal of Neurology;2024-06-13

2. Casein kinase 1 inhibitor avoids TDP-43 pathology propagation in a patient-derived cellular model of amyotrophic lateral sclerosis;Neurobiology of Disease;2024-03

3. Progranulin haploinsufficiency mediates cytoplasmic TDP-43 aggregation with lysosomal abnormalities in human microglia;Journal of Neuroinflammation;2024-02-13

4. Druggable cavities and allosteric modulators of the cell division cycle 7 (CDC7) kinase;Journal of Enzyme Inhibition and Medicinal Chemistry;2024-01-11

5. The key role of TDP-43 in amyotrophic lateral sclerosis propagation and the disease-modifying profile of CK-1 inhibitors;2023-09-15

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