A novel assay to measure B cell responses to keyhole limpet haemocyanin vaccination in healthy volunteers and subjects with systemic lupus erythematosus-Reference-Cited by-同舟云学术

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A novel assay to measure B cell responses to keyhole limpet haemocyanin vaccination in healthy volunteers and subjects with systemic lupus erythematosus

Published:2013-07-23 Issue:2 Volume:76 Page:188-202
ISSN:0306-5251
Container-title:British Journal of Clinical Pharmacology
language:en
Short-container-title:Br J Clin Pharmacol

Author:

Ferbas John¹,Belouski Shelley S.¹,Horner Michelle²,Kaliyaperumal Arunan¹,Chen Li¹,Boyce Malcolm³,Colaço C. Bernie³,McHugh Neil⁴,Quick Vanessa³,Nicholl Richard J.¹,Siu Gerald⁵,Chung James¹

Affiliation:

1. Department of Medical Sciences; Amgen, Inc; Thousand Oaks; CA; USA

2. Department of Comparative Biology and Safety Sciences; Amgen, Inc; Thousand Oaks; CA; USA

3. Hammersmith Medicines Research; London; UK

4. Royal National Hospital for Rheumatic Diseases; Bath; UK

5. Department of Inflammation; Amgen, Inc; Thousand Oaks; CA; USA

Publisher

Wiley

Subject

Pharmacology (medical),Pharmacology

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1111/bcp.12172/fullpdf

Reference54 articles.

1. Therapy of autoimmune diseases: clinical trials and new biologics;Nepom;Curr Opin Immunol,2002

2. Toxicity and monitoring of immunosuppressive therapy used in systemic autoimmune diseases;Meyer;Clin Chest Med,2010

3. B cells as therpautic targets for rheumatic diseases;Looney;Curr Opin Rheumatol,2004

4. Understanding autoimmune disease: new targets for drug discovery;Balague;Drug Discov Today,2009

5. Cytokine inhibitors in rheumatoid arthritis and other autoimmune diseases;Williams;Curr Opin Pharmacol,2007

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1. Evaluation of single-strain Prevotella histicola on KLH-driven immune responses in healthy volunteers: A randomized controlled trial with EDP1815;Medicine in Microecology;2024-03

2. Impact of oral administration of single strain Lactococcus lactis spp. cremoris on immune responses to keyhole limpet hemocyanin immunization and gut microbiota: A randomized placebo-controlled trial in healthy volunteers;Frontiers in Immunology;2022-12-07

3. In vivo human keyhole limpet hemocyanin challenge in early phase drug development: A systematic review;Clinical and Translational Science;2022-11-24

4. Characterization of KLH-driven immune responses in clinical studies: A systematic review;Frontiers in Drug Discovery;2022-10-25

5. OX40L Inhibition Suppresses KLH‐driven Immune Responses in Healthy Volunteers: A Randomized Controlled Trial Demonstrating Proof‐of‐Pharmacology for KY1005;Clinical Pharmacology & Therapeutics;2022-03

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