In vivo human keyhole limpet hemocyanin challenge in early phase drug development: A systematic review-Reference-Cited by-同舟云学术

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In vivo human keyhole limpet hemocyanin challenge in early phase drug development: A systematic review

Published:2022-11-24 Issue:3 Volume:16 Page:357-382
ISSN:1752-8054
Container-title:Clinical and Translational Science
language:en
Short-container-title:Clinical Translational Sci

Author:

Drennan Philip G.¹²^ORCID,Karponis Dimitrios²,Richards Duncan³^ORCID,Coles Mark¹,Fullerton James N.²³^ORCID

Affiliation:

1. Kennedy Institute of Rheumatology, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Medicine University of Oxford Oxford UK

2. Oxford University Hospitals NHS Foundation Trust Oxford UK

3. Botnar Research Centre, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Medicine University of Oxford Oxford UK

Funder

University of Kentucky

Kennedy Trust for Rheumatology Research

Publisher

Wiley

Subject

General Pharmacology, Toxicology and Pharmaceutics,General Biochemistry, Genetics and Molecular Biology,General Medicine,General Neuroscience

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1111/cts.13457

Reference86 articles.

1. Estimated Research and Development Investment Needed to Bring a New Medicine to Market, 2009-2018

2. Breaking Eroom’s Law

3. Lessons learned from the fate of AstraZeneca's drug pipeline: a five-dimensional framework

4. Reviving an R&D pipeline: a step change in the Phase II success rate

5. Trends in clinical success rates and therapeutic focus

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