Special considerations for clinical trials in fibrodysplasia ossificans progressiva (FOP)

Author:

Hsiao Edward C.1ORCID,Di Rocco Maja2,Cali Amanda3,Zasloff Michael4,Al Mukaddam Mona5,Pignolo Robert J.6,Grunwald Zvi7,Netelenbos Coen8,Keen Richard9,Baujat Genevieve10,Brown Matthew A.11,Cho Tae‐Joon12,De Cunto Carmen13,Delai Patricia14,Haga Nobuhiko15,Morhart Rolf16,Scott Christiaan17,Zhang Keqin18,Diecidue Robert J.19,Friedman Clive S.20,Kaplan Fredrick S.21,Eekhoff Elisabeth M.W.8

Affiliation:

1. Division of Endocrinology and Metabolism, and the Institute for Human Genetics, Department of MedicineUniversity of California San Francisco CA USA

2. Unit of Rare Diseases, Department of PediatricsIRCCS Giannina Gaslini Institute Genoa Italy

3. Radiant Hope Foundation and the Ian Cali FOP Research Fund, PENN MedicineCenter for Research in FOP & Related Disorders

4. Departments of Orthopaedic Surgery and Genetics, The Center for Research in FOP & Related DisordersUniversity of Pennsylvania School of Medicine; and MedStar Georgetown Transplant Institute Georgetown University School of Medicine Washington DC USA

5. Division of Endocrinology, Diabetes and Metabolism, Departments of Medicine and Orthopaedic SurgeryUniversity of Pennsylvania School of Medicine Philadelphia PA USA

6. Department of MedicineMayo Clinic Rochester MN USA

7. Department of AnesthesiologyThomas Jefferson University Philadelphia PA USA

8. Department of Internal Medicine section Endocrinology, Amsterdam Bone CenterAmsterdam University Medical Centers location VUmc Amsterdam the Netherlands

9. Royal National Orthopaedic Hospital Stanmore UK

10. Centre de Référence Maladies Osseuses Constitutionnelles, Departement de GénétiqueHôpital Necker‐Enfants Malades, Institut Imagine Paris France

11. Institute of Health and Biomedical Innovation, Queensland University of Technology, Translational Research Institute Woolloongabba QLD Australia

12. Division of Pediatric OrthopaedicsSeoul National University Children's Hospital Seoul South Korea

13. Pediatric Rheumatology Section, Department of PediatricsHospital Italiano de Buenos Aires Ciudad Autónoma de Buenos Aires Argentina

14. Hospital Israelita Albert Einstein, Instituto de Ensino e Pesquisa São Paulo‐SP Brazil

15. Department of Rehabilitation Medicine, Graduate School of MedicineUniversity of Tokyo Tokyo Japan

16. Department of Pediatrics, Klinikum Garmisch‐Partenkirchen GmbH Garmisch‐Partenkirchen Germany

17. Paediatric Rheumatology, Red Cross Children's HospitalUniversity of Cape Town Cape Town South Africa

18. Department of Endocrinology, Tongji HospitalShanghai Tongji University Shanghai China

19. Sidney Kimmel Medical CollegeThomas Jefferson University Philadelphia PA USA

20. Schulich School of Medicine and Dentistry, Pediatric Oral Health and Dentistry London ON Canada

21. Departments of Medicine & Orthopaedic Surgery, Center for Research in FOP & Related Disorders, The Perelman School of MedicineUniversity of Pennsylvania Philadelphia PA USA

Funder

Department of Medicine, University of California, San Francisco

Publisher

Wiley

Subject

Pharmacology (medical),Pharmacology

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