Transient depletion of CD4+ CD25+regulatory T cells results in multiple autoimmune diseases in wild-type and B-cell-deficient NOD mice

Author:

Ellis Jason S.1,Wan Xiaoxiao2,Braley-Mullen Helen

Affiliation:

1. Department of Medicine; University of Missouri School of Medicine; Columbia; MO; USA

2. Department of Molecular Microbiology & Immunology; University of Missouri School of Medicine; Columbia; MO; USA

Publisher

Wiley

Subject

Immunology,Immunology and Allergy

Reference51 articles.

1. I-Ag7-mediated antigen presentation by B lymphocytes is critical in overcoming a checkpoint in T cell tolerance to islet beta cells of nonobese diabetic mice;Noorchashm;J Immunol,1999

2. B lymphocytes are critical antigen-presenting cells for the initiation of T cell-mediated autoimmune diabetes in nonobese diabetic mice;Serreze;J Immunol,1998

3. Investigation of the role of B-cells in type 1 diabetes in the NOD mouse;Wong;Diabetes,2004

4. Loss of intra-islet CD20 expression may complicate efficacy of B-cell-directed type 1 diabetes therapies;Serreze;Diabetes,2011

5. Early requirement for B cells for development of spontaneous autoimmune thyroiditis in NOD.H-2h4 mice;Braley-Mullen;J Immunol,2000

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