Loss of Intra-Islet CD20 Expression May Complicate Efficacy of B-Cell–Directed Type 1 Diabetes Therapies
Author:
Affiliation:
1. The Jackson Laboratory, Bar Harbor, Maine
2. Biogen Idec, San Diego, California
3. Department of Pediatrics, University of Florida, Gainesville, Florida
4. Department of Pathology, University of Florida, Gainesville, Florida
Abstract
Publisher
American Diabetes Association
Subject
Endocrinology, Diabetes and Metabolism,Internal Medicine
Link
https://journals.org/diabetes/diabetes/article-pdf/60/11/2914/400738/2914.pdf
Reference44 articles.
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2. B lymphocytes are crucial antigen-presenting cells in the pathogenic autoimmune response to GAD65 antigen in nonobese diabetic mice;Falcone;J Immunol,1998
3. I-Ag7-mediated antigen presentation by B lymphocytes is critical in overcoming a checkpoint in T cell tolerance to islet β cells of nonobese diabetic mice;Noorchashm;J Immunol,1999
4. B lymphocytes are critical antigen-presenting cells for the initiation of T cell-mediated autoimmune diabetes in nonobese diabetic mice;Serreze;J Immunol,1998
5. B cell specificity contributes to the outcome of diabetes in nonobese diabetic mice;Hulbert;J Immunol,2001
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