Cytokine release syndrome and neurotoxicity after CD19 chimeric antigen receptor-modified (CAR-) T cell therapy

Author:

Hay Kevin A.12ORCID

Affiliation:

1. Department of Medicine; University of British Columbia; Vancouver BC USA

2. Fred Hutchinson Cancer Research Center; Seattle WA USA

Publisher

Wiley

Subject

Hematology

Reference79 articles.

1. Updated safety and long term clinical outcomes in TRANSCEND NHL 001, pivotal trial of lisocabtagene maraleucel (JCAR017) in R/R aggressive NHL;Abramson;Journal of Clinical Oncology,2018

2. T cells expressing an anti-B-cell maturation antigen chimeric antigen receptor cause remissions of multiple myeloma;Ali;Blood,2016

3. Pericytes regulate the blood-brain barrier;Armulik;Nature,2010

4. Interleukin 6-mediated endothelial barrier disturbances can be attenuated by blockade of the IL6 receptor expressed in brain microvascular endothelial cells;Blecharz-Lang;Translational Stroke Research,2018

5. The effect of dexamethasone on polyclonal T cell activation and redirected target cell lysis as induced by a CD19/CD3-bispecific single-chain antibody construct;Brandl;Cancer Immunology, Immunotherapy,2007

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