Pharmacokinetic-pharmacodynamic studies of the 11β-hydroxysteroid dehydrogenase type 1 inhibitor MK-0916 in healthy subjects
Author:
Affiliation:
1. Merck Sharp & Dohme Corp.; Whitehouse Station NJ USA
2. MSD Europe; Brussels Belgium
3. Clinical Pharmacology Unit; SGS Life Science Services; Antwerp Belgium
Publisher
Wiley
Subject
Pharmacology (medical),Pharmacology
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1111/bcp.12131/fullpdf
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3. Obesity and corticosteroids: 11beta-hydroxysteroid type 1 as a cause and therapeutic target in metabolic disease;Morton;Mol Cell Endocrinol,2010
4. Executive summary of the third report of the national cholesterol education program (NCEP) expert panel on detection, evaluation, and treatment of high blood cholesterol in adults (Adult Treatment Panel III);Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults;JAMA,2001
5. Minireview: 11β-hydroxysteroid dehydrogenase type 1- a tissue-specific amplifier of glucocorticoid action;Seckl;Endocrinology,2001
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