Discovery of novel inhibitor of 11 beta-hydroxysteroid dehydrogenase type 1 using in silico structure-based screening approach for the treatment of type 2 diabetes
Author:
Publisher
Springer Science and Business Media LLC
Subject
Endocrinology, Diabetes and Metabolism,Internal Medicine
Link
https://link.springer.com/content/pdf/10.1007/s40200-023-01191-8.pdf
Reference60 articles.
1. Barbot M, Ceccato F, Scaroni C. Diabetes Mellitus secondary to Cushing’s Disease. Front Endocrinol (Lausanne). 2018;9:284.
2. Steffensen C, Dekkers OM, Lyhne J, Pedersen BG, Rasmussen F, Rungby J, et al. Hypercortisolism in newly diagnosed type 2 diabetes: a prospective study of 384 newly diagnosed patients. Horm Metab Res. 2019;51:62–8.
3. Aulinas A, Valassi E, Webb SM. Prognosis of patients treated for Cushing syndrome. Endocrinol Nutr. 2014;61(1):52–61.
4. Tomlinson JW, Walker EA, Bujalska IJ, Draper N, Lavery GG, Cooper MS, et al. 11β-Hydroxysteroid dehydrogenase type 1: a tissue-specific regulator of glucocorticoid response. Endocr Rev. 2004;2:831–66.
5. Peng K, Pan Y, Li J, Khan Z, Fan M, Yin H, et al. 11β-Hydroxysteroid dehydrogenase type 1(11β-HSD1) mediates insulin resistance through JNK activation in adipocytes. Sci Rep. 2016;6:37160.
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