Clinical evaluation of the potential drug–drug interactions of savolitinib: Interaction with rifampicin, itraconazole, famotidine or midazolam

Author:

Ren Song1,Vishwanathan Karthick2ORCID,Cantarini Mireille3,Frewer Paul4,Hara Indira5,Scarfe Graeme6,Burke Wendy7,Schalkwijk Stein8ORCID,Li Yan9,Han David10,Goldwater Ronald11

Affiliation:

1. Clinical Pharmacology & Quantitative Pharmacology BioPharmaceuticals R&D, AstraZeneca Gaithersburg Maryland USA

2. Clinical Pharmacology & Quantitative Pharmacology CPSS, R&D, AstraZeneca Boston Massachusetts USA

3. Oncology Late Development Oncology R&D, AstraZeneca Cambridge UK

4. Oncology Biometrics, Oncology R&D, AstraZeneca Cambridge UK

5. Patient Safety, Oncology TA, MedImmune‐AstraZeneca Cambridge UK

6. Drug Metabolism and Pharmacokinetics, Oncology R&D, Research & Early Development, AstraZeneca Cambridge UK

7. Covance Clinical Research Unit Leeds UK

8. Clinical Pharmacology & Quantitative Pharmacology CPSS, R&D, AstraZeneca Cambridge UK

9. Integrated Bioanalysis, Clinical Pharmacology & Quantitative Pharmacology BioPharmaceuticals R&D, AstraZeneca Boston Massachusetts USA

10. Parexel International Glendale California USA

11. Parexel International Baltimore Maryland USA

Funder

AstraZeneca

Publisher

Wiley

Subject

Pharmacology (medical),Pharmacology

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