Pharmacokinetic variability of valproate in women of childbearing age

Author:

Johannessen Landmark Cecilie123,Burns Margrete Larsen3,Baftiu Arton1,Farmen Anette Huuse4,Lossius Morten I.2,Johannessen Svein I.23,Tomson Torbjörn5

Affiliation:

1. Program for Pharmacy; Department of Life Sciences and Health; Faculty of Health Sciences; Oslo and Akershus University College of Applied Sciences; Oslo Norway

2. National Center for Epilepsy; Oslo University Hospital; Sandvika Norway

3. Department of Pharmacology; Oslo University Hospital; Oslo Norway

4. Department of Neurology; Innlandet Hospital Trust; Lillehammer Norway

5. Department of Clinical Neuroscience; Karolinska Institute; Stockholm Sweden

Publisher

Wiley

Subject

Neurology (clinical),Neurology

Reference17 articles.

1. European Medicines Agency PRAC recommends strengthening the restrictions on the use of valproate in women and girls 2014 http://www.ema.europa.eu/docs/en_GB/document_library/Press_release/2014/10/WC500175208.pdf

2. European Medicines Agency New review of valproate use in pregnancy and women of childbearing age

3. Valproate in the treatment of epilepsy in women and girls: recommendations from a joint Task Force of ILAE-Commission on European Affairs and European Academy of Neurology (EAN);Tomson;Epilepsia,2015

4. Commentary: Valproate in the treatment of epilepsy in women and girls: the need for recommendations;Tomson;Epilepsia,2015

5. Dose-dependent risk of malformations with antiepileptic drugs: an analysis of data from the EURAP epilepsy and pregnancy registry;Tomson;Lancet Neurol,2011

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