Dimethyl itaconate protects against fungal keratitis by activating the Nrf2/HO‐1 signaling pathway
Author:
Affiliation:
1. Department of Ophthalmology The Affiliated Hospital of Qingdao University Qingdao China
2. Department of Medicine Qingdao University Qingdao China
Funder
Natural Science Foundation of Shandong Province
National Natural Science Foundation of China
Publisher
Wiley
Subject
Cell Biology,Immunology,Immunology and Allergy
Link
https://onlinelibrary.wiley.com/doi/pdf/10.1111/imcb.12316
Reference34 articles.
1. Spectrum of Fungal Keratitis in North China
2. Indoleamine 2,3-Dioxygenase Is Involved in the Inflammation Response of Corneal Epithelial Cells to Aspergillus fumigatus Infections
3. A Role for the Krebs Cycle Intermediate Citrate in Metabolic Reprogramming in Innate Immunity and Inflammation
4. Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1
5. Itaconate: an emerging determinant of inflammation in activated macrophages
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