Evaluation of the safety and pharmacokinetics of a fast-acting recombinant FVIIa analogue, NN1731, in healthy male subjects
Author:
Publisher
Wiley
Subject
Hematology
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1111/j.1538-7836.2008.03253.x/fullpdf
Reference10 articles.
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2. Platelet activity of high-dose factor VIIa is independent of tissue factor;Monroe;Br J Haematol,1997
3. Rational design of coagulation factor VIIa variants with substantially increased intrinsic activity;Persson;Proc Natl Acad Sci USA,2001
4. A variant of recombinant factor VIIa with enhanced procoagulant and antifibrinolytic activities in an in vitro model of hemophilia;Allen;Arterioscler Thromb Vasc Biol,2007
5. Factor VIIa analogue (V158D/E296V/M298Q-FVIIa) normalises clot formation in whole blood from patients with severe haemophilia A;Sørensen;Br J Haematol,2007
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