Immunogenicity Lessons Learned from the Clinical Development of Vatreptacog Alfa, A Recombinant Activated Factor VII Analog, in Hemophilia with Inhibitors
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Publisher
Springer International Publishing
Link
http://link.springer.com/content/pdf/10.1007/7355_2016_1
Reference98 articles.
1. Lentz SR, Ehrenforth S, Karim FA, Matsushita T, Weldingh KN, Windyga J, Mahlangu JN, and adeptTM2 Investigators (2014) Recombinant factor VIIa analog in the management of hemophilia with inhibitors: results from a multicenter, randomized, controlled trial of vatreptacog alfa. J Thromb Haemost 12(8):1244–1253
2. de Paula EV, Kavakli K, Mahlangu J, Ayob Y, Lentz SR, Morfini M, Nemes L, Šalek SZ, Shima M, Windyga J, Ehrenforth S, Chuansumrit A, and 1804 (adept™1) Investigators (2012) Recombinant factor VIIa analog (vatreptacog alfa [activated]) for treatment of joint bleeds in hemophilia patients with inhibitors: a randomized controlled trial. J Thromb Haemost 10(1):81–89
3. Persson E, Olsen OH, Bjørn SE, Ezban M (2012) Vatreptacog alfa from conception to clinical proof of concept. Semin Thromb Hemost 38(3):274–281
4. Mahlangu JN, Coetzee MJ, Laffan M, Windyga J, Yee TT, Schroeder J, Haaning J, Siegel JE, Lemm G (2012) Phase I, randomized, double-blind, placebo-controlled, single-dose escalation study of the recombinant factor VIIa variant BAY 86–6150 in hemophilia. J Thromb Haemost 10(5):773–780
5. Pipe S (2009) Antihemophilic factor (recombinant) plasma/albumin-free method for the management and prevention of bleeding episodes in patients with hemophilia A. Biologics 3:117–125
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