Identification of a novel, nanobody-induced, mechanism of TAFI inactivation and its in vivo application-Reference-Cited by-同舟云学术

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Identification of a novel, nanobody-induced, mechanism of TAFI inactivation and its in vivo application

Published:2014-02 Issue:2 Volume:12 Page:229-236
ISSN:1538-7933
Container-title:Journal of Thrombosis and Haemostasis
language:en
Short-container-title:J Thromb Haemost

Author:

Hendrickx M. L. V.¹,Zatloukalova M.¹,Hassanzadeh-Ghassabeh G.²³,Muyldermans S.²⁴,Gils A.¹,Declerck P. J.¹

Affiliation:

1. Laboratory for Therapeutic and Diagnostic Antibodies; Department of Pharmaceutical and Pharmacological Sciences; KU Leuven; Brussels Belgium

2. Laboratory of Cellular and Molecular Immunology; Faculty of Sciences; Vrije Universiteit Brussel; Brussels Belgium

3. Nanobody Service facility (NSF); VIB; Brussels Belgium

4. VIB Department of Structural Biology; Brussels Belgium

Funder

Scientific Research Flanders

Publisher

Wiley

Subject

Hematology

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1111/jth.12473/fullpdf

Reference22 articles.

1. Thrombin-activatable fibrinolysis inhibitor (TAFI, plasma procarboxypeptidase B, procarboxypeptidase R, procarboxypeptidase U);Bouma;Thromb Res,2001

2. Plasma TAFI levels influence the clot lysis time in healthy individuals in the presence of an intact intrinsic pathway of coagulation;Mosnier;Thromb Haemost,1998

3. The profibrinolytic effect of activated protein C in clots formed from plasma is TAFI-dependent;Bajzar;Blood,1996

4. Purification and characterization of TAFI, a thrombin-activable fibrinolysis inhibitor;Bajzar;J Biol Chem,1995

5. Proteolytic activation of purified human procarboxypeptidase U;Schatteman;Clin Chim Acta,2000

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2. Fibrinogen and Antifibrinolytic Proteins: Interactions and Future Therapeutics;International Journal of Molecular Sciences;2021-11-21

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4. Endogenous fibrinolysis inhibitors in acute coronary syndrome;American Heart Journal Plus: Cardiology Research and Practice;2021-10

5. S62798, a potent TAFIa inhibitor, accelerates endogenous fibrinolysis in a murine model of pulmonary thromboembolism;Thrombosis Research;2021-08

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