GSK256073, a selective agonist of G-protein coupled receptor 109A (GPR109A) reduces serum glucose in subjects with type 2 diabetes mellitus-Reference-Cited by-同舟云学术

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GSK256073, a selective agonist of G-protein coupled receptor 109A (GPR109A) reduces serum glucose in subjects with type 2 diabetes mellitus

Published:2013-06-12 Issue:11 Volume:15 Page:1013-1021
ISSN:1462-8902
Container-title:Diabetes, Obesity and Metabolism
language:en
Short-container-title:Diabetes Obes Metab

Author:

Dobbins R. L.¹,Shearn S. P.²,Byerly R. L.¹,Gao F. F.³,Mahar K. M.³,Napolitano A.⁴,Nachbaur G. J.⁵,Le Monnier de Gouville A. -C.⁵

Affiliation:

1. GlaxoSmithKline, Drug Discovery; Research Triangle Park; NC; USA

2. GlaxoSmithKline, Drug Discovery; Upper Merion; PA; USA

3. GlaxoSmithKline, Quantitative Sciences; Upper Merion; PA; USA

4. GlaxoSmithKline, Clinical Unit Cambridge; Cambridge; UK

5. GlaxoSmithKline, Drug Discovery; Les Ulis; France

Publisher

Wiley

Subject

Endocrinology,Endocrinology, Diabetes and Metabolism,Internal Medicine

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1111/dom.12132/fullpdf

Reference36 articles.

1. Insulin resistance, lipid and fatty acid concentrations in 867 healthy Europeans. European Group for the Study of Insulin Resistance (EGIR);Baldeweg;Eur J Clin Invest,2000

2. A high concentration of fasting plasma non-esterified fatty acids is a risk factor for the development of NIDDM;Paolisso;Diabetologia,1995

3. Banting lecture 2001: dysregulation of fatty acid metabolism in the etiology of type 2 diabetes;McGarry;Diabetes,2002

4. The glucose fatty-acid cycle. Its role in insulin sensitivity and the metabolic disturbances of diabetes mellitus;Randle;Lancet,1963

5. Measurement of plasma glucose, free fatty acid, lactate, and insulin for 24 h in patients with NIDDM;Reaven;Diabetes,1988

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