Functional characterization of the antiepileptic drug candidate, padsevonil, on GABAAreceptors
Author:
Affiliation:
1. Neurosciences Therapeutic Area UCB Pharma Braine l’Alleud Belgium
Funder
UCB Pharma
Publisher
Wiley
Subject
Neurology (clinical),Neurology
Link
https://onlinelibrary.wiley.com/doi/pdf/10.1111/epi.16497
Reference33 articles.
1. Benefit of combination therapy in epilepsy: A review of the preclinical evidence with levetiracetam
2. Pharmacological Profile of the Novel Antiepileptic Drug Candidate Padsevonil: Interactions with Synaptic Vesicle 2 Proteins and the GABAA Receptor
3. Modulation of the conformational state of the SV2A protein by an allosteric mechanism as evidenced by ligand binding assays
4. Evidence for a differential interaction of brivaracetam and levetiracetam with the synaptic vesicle 2A protein
5. Brivaracetam Differentially Affects Voltage‐Gated Sodium Currents Without Impairing Sustained Repetitive Firing in Neurons
Cited by 10 articles. 订阅此论文施引文献 订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献
1. Padsevonil suppresses seizures without inducing cell death in neonatal rats;Pharmacological Reports;2024-07-19
2. Overview of preclinical and clinical studies investigating pharmacokinetics and drug–drug interactions of padsevonil;Expert Opinion on Drug Metabolism & Toxicology;2024-07-09
3. Decoding Epileptic Seizures: Exploring In Vitro Approaches to Unravel Pathophysiology and Propel Future Therapeutic Breakthroughs;Biomedical Materials & Devices;2024-02-27
4. Established and emerging GABAA receptor pharmacotherapy for epilepsy;Frontiers in Pharmacology;2024-02-21
5. Clinical Bridging Studies and Modeling Approach for Implementation of a Patient Centric Sampling Technique in Padsevonil Clinical Development;The AAPS Journal;2023-11-16
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线，采集、加工和组织学术论文而形成的新型学术文献查询和分析系统，可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容，当前同舟云学术共收录了国内外主流学术期刊6万余种，收集的期刊论文及会议论文总量共计约1.5亿篇，并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询！咨询电话：010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3