Biolink Model: A universal schema for knowledge graphs in clinical, biomedical, and translational science

Author:

Unni Deepak R.12ORCID,Moxon Sierra A. T.2ORCID,Bada Michael3ORCID,Brush Matthew3ORCID,Bruskiewich Richard4ORCID,Caufield J. Harry2,Clemons Paul A.5ORCID,Dancik Vlado5ORCID,Dumontier Michel6ORCID,Fecho Karamarie7ORCID,Glusman Gustavo8ORCID,Hadlock Jennifer J.8ORCID,Harris Nomi L.2ORCID,Joshi Arpita8ORCID,Putman Tim3ORCID,Qin Guangrong8ORCID,Ramsey Stephen A.9ORCID,Shefchek Kent A.3ORCID,Solbrig Harold10ORCID,Soman Karthik11ORCID,Thessen Anne E.3ORCID,Haendel Melissa A.3ORCID,Bizon Chris7ORCID,Mungall Christopher J.2ORCID,Acevedo Liliana,Ahalt Stanley C.,Alden John,Alkanaq Ahmed,Amin Nada,Avila Ricardo,Balhoff Jim,Baranzini Sergio E.,Baumgartner Andrew,Baumgartner William,Belhu Basazin,Brandes MacKenzie,Brandon Namdi,Burtt Noel,Byrd William,Callaghan Jackson,Cano Marco Alvarado,Carrell Steven,Celebi Remzi,Champion James,Chen Zhehuan,Chen Mei‐Jan,Chung Lawrence,Cohen Kevin,Conlin Tom,Corkill Dan,Costanzo Maria,Cox Steven,Crouse Andrew,Crowder Camerron,Crumbley Mary E.,Dai Cheng,Dančík Vlado,De Miranda Azevedo Ricardo,Deutsch Eric,Dougherty Jennifer,Duby Marc P.,Duvvuri Venkata,Edwards Stephen,Emonet Vincent,Fehrmann Nathaniel,Flannick Jason,Foksinska Aleksandra M.,Gardner Vicki,Gatica Edgar,Glen Amy,Goel Prateek,Gormley Joseph,Greyber Alon,Haaland Perry,Hanspers Kristina,He Kaiwen,He Kaiwen,Henrickson Jeff,Hinderer Eugene W.,Hoatlin Maureen,Hoffman Andrew,Huang Sui,Huang Conrad,Hubal Robert,Huellas‐Bruskiewicz Kenneth,Huls Forest B.,Hunter Lawrence,Hyde Greg,Issabekova Tursynay,Jarrell Matthew,Jenkins Lindsay,Johs Adam,Kang Jimin,Kanwar Richa,Kebede Yaphet,Kim Keum Joo,Kluge Alexandria,Knowles Michael,Koesterer Ryan,Korn Daniel,Koslicki David,Krishnamurthy Ashok,Kvarfordt Lindsey,Lee Jay,Leigh Margaret,Lin Jason,Liu Zheng,Liu Shaopeng,Ma Chunyu,Magis Andrew,Mamidi Tarun,Mandal Meisha,Mantilla Michelle,Massung Jeffrey,Mauldin Denise,McClelland Jason,McMurry Julie,Mease Philip,Mendoza Luis,Mersmann Marian,Mesbah Abrar,Might Matthew,Morton Kenny,Muller Sandrine,Muluka Arun Teja,Osborne John,Owen Phil,Patton Michael,Peden David B.,Peene R. Carter,Persaud Bria,Pfaff Emily,Pico Alexander,Pollard Elizabeth,Price Guthrie,Raj Shruti,Reilly Jason,Riutta Anders,Roach Jared,Roper Ryan T.,Rosenblatt Greg,Rubin Irit,Rucka Sienna,Rudavsky‐Brody Nathaniel,Sakaguchi Rayn,Santos Eugene,Schaper Kevin,Schmitt Charles P.,Schurman Shepherd,Scott Erik,Seitanakis Sarah,Sharma Priya,Shmulevich Ilya,Shrestha Manil,Shrivastava Shalki,Sinha Meghamala,Smith Brett,Southall Noel,Southern Nicholas,Stillwell Lisa,Strasser Michael " Michi",Su Andrew I.,Ta Casey,Thessen Anne E.,Tinglin Jillian,Tonstad Lucas,Tran‐Nguyen Thi,Tropsha Alexander,Vaidya Gaurav,Veenhuis Luke,Viola Adam,von Grotthuss Marcin,Wang Max,Wang Patrick,Watkins Paul B.,Weber Rosina,Wei Qi,Weng Chunhua,Whitlock Jordan,Williams Mark D.,Williams Andrew,Womack Finn,Wood Erica,Wu Chunlei,Xin Jiwen Kevin,Xu Hao,Xu Colleen,Yakaboski Chase,Yao Yao,Yi Hong,Yilmaz Arif,Zheng Marissa,Zhou Xinghua,Zhou Eric,Zhu Qian,Zisk Tom,

Affiliation:

1. Genome Biology Unit, European Molecular Biology Laboratory Heidelberg Germany

2. Division of Environmental Genomics and Systems Biology Lawrence Berkeley National Laboratory Berkeley California USA

3. Center for Health AI University of Colorado Anschutz Medical Campus Aurora Colorado USA

4. Star Informatics Sooke British Columbia Canada

5. Chemical Biology and Therapeutics Science Program Broad Institute Cambridge Massachusetts USA

6. Institute of Data Science Maastricht University Maastricht The Netherlands

7. Renaissance Computing Institute University of North Carolina at Chapel Hill Chapel Hill North Carolina USA

8. Institute for Systems Biology Seattle Washington USA

9. Department of Biomedical Sciences Oregon State University Corvallis Oregon USA

10. Johns Hopkins University Baltimore Maryland USA

11. Department of Neurology University of California San Francisco San Francisco California USA

Funder

U.S. Department of Energy

National Human Genome Research Institute

National Institutes of Health

Publisher

Wiley

Subject

General Pharmacology, Toxicology and Pharmaceutics,General Biochemistry, Genetics and Molecular Biology,General Medicine,General Neuroscience

Reference26 articles.

1. National Physical Laboratory.Symposium. International Conference on Machine Translation of Languages and Applied Language Analysis.National Physical Laboratory;1961. Accessed March 03 2022.https://market.android.com/details?id=book‐dTTawQEACAAJ

2. Wikidata

3. VasilakesJA RizviR ZhangR.Annotated Semantic Predications from SemMedDB;2018. Accessed March 03 2022.https://conservancy.umn.edu/handle/11299/194965

4. Systematic integration of biomedical knowledge prioritizes drugs for repurposing

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