Evaluation of the Influence of Three Newly Developed Bispyridinium Anti-nicotinic Compounds (MB408, MB442, MB444) on the Efficacy of Antidotal Treatment of Nerve Agent Poisoning in Mice-Reference-Cited by-同舟云学术

Evaluation of the Influence of Three Newly Developed Bispyridinium Anti-nicotinic Compounds (MB408, MB442, MB444) on the Efficacy of Antidotal Treatment of Nerve Agent Poisoning in Mice

Published:2017-12-05 Issue:4 Volume:122 Page:429-435
ISSN:1742-7835
Container-title:Basic & Clinical Pharmacology & Toxicology
language:en
Short-container-title:Basic Clin Pharmacol Toxicol

Author:

Kassa Jiri¹,Timperley Christopher M.²,Bird Mike²,Williams Rebecca L.²,Green A. Christopher²,Tattersall John E. H.²

Affiliation:

1. Department of Toxicology and Military Pharmacy; Faculty of Military Health Sciences; Hradec Kralove Czech Republic

2. Chemical, Biological and Radiological Division; Defence Science and Technology Laboratory (Dstl); Porton Down Salisbury UK

Funder

Ministry of Defence

‘Long-term Organization Development Plan - Medical Aspects of Weapons of Mass Destruction’

Publisher

Wiley

Subject

Pharmacology,Toxicology,General Medicine

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1111/bcpt.12935/fullpdf

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3. Acetylcholinesterase inhibitors: pharmacology and toxicology;Colovic;Curr Neuropharmacol,2013

4. Testing of antidotes for organophosphorus compounds: experimental procedures and clinical reality;Eyer;Toxicology,2007

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4. Some benefit from non-oximes MB408, MB442 and MB444 in combination with the oximes HI-6 or obidoxime and atropine in antidoting sarin or cyclosarin poisoned mice;Toxicology;2018-09