A randomised, controlled, crossover study to investigate the safety and response of 1R,2S-methoxamine hydrochloride (NRL001) on anal function in healthy volunteers

Author:

Simpson J. A. D.1,Bush D.2,Gruss H. J.3,Jacobs A.4,Pediconi C.5,Scholefield J. H.6

Affiliation:

1. Division of Surgery; University of Nottingham; Nottingham UK

2. Division of Gastrointestinal Surgery; University of Nottingham; Nottingham UK

3. Medical & Safety Services; ICON Clinical Research; Eastleigh UK

4. Dianthus Medical Limited; London UK

5. Norgine Limited; Uxbridge UK

6. Division of Surgery; Queen's Medical Centre; University Hospital Nottingham; Nottingham UK

Publisher

Wiley

Subject

Gastroenterology

Reference17 articles.

1. Rome III Diagnostic Criteria for Functional Gastrointestinal Disorders http://www.romecriteria.org/assets/pdf/19_RomeIII_apA_885-898.pdf

2. Faecal incontinence: the ‘Cinderella’ disorder;Scholefield;Colorectal Dis,2014

3. Diagnostic evaluation of patients with faecal incontinence at a specialist institution;Mimura;Dig Surg,2004

4. New treatment for faecal incontinence using zinc-aluminium ointment: a double-blind randomized trial;Pinedo;Colorectal Dis,2012

5. Are topical oestrogens useful in faecal incontinence? Double-blind randomized trial;Pinedo;Colorectal Dis,2009

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