1. Institute of Pharmacology; School of Medicine, Catholic University of the Sacred Heart; L.go F. Vito 1 00168 Rome Italy
2. Department of Internal Medicine; School of Medicine, Catholic University of the Sacred Heart; L.go F. Vito 1 00168 Rome Italy
3. Department of Clinical and Experimental Medicine; University of Sassari; V.le S. Pietro, 8 07100 Sassari Italy