The isomerase and hydratase reaction mechanism of the crotonase active site of the multifunctional enzyme (type-1), as deduced from structures of complexes with 3S-hydroxy-acyl-CoA
Author:
Affiliation:
1. Biocenter Oulu and Department of Biochemistry; University of Oulu; Finland
2. Theodor-Boveri-Institut für Biowissenschaften (Biozentrum) der Universität Würzburg; Germany
Publisher
Wiley
Subject
Cell Biology,Molecular Biology,Biochemistry
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1111/febs.12150/fullpdf
Reference57 articles.
1. Peroxisomal beta-oxidation - a metabolic pathway with multiple functions;Poirier;Biochim Biophys Acta,2006
2. Organization of the multifunctional enzyme type 1: interaction between N- and C-terminal domains is required for the hydratase-1/isomerase activity;Kiema;Biochem J,2002
3. The crotonase superfamily: divergently related enzymes that catalyze different reactions involving acyl coenzyme a thioesters;Holden;Acc Chem Res,2001
4. Mechanisms and structures of crotonase superfamily enzymes - how nature controls enolate and oxyanion reactivity;Hamed;Cell Mol Life Sci,2008
5. Sequestration of the active site by interdomain shifting. Crystallographic and spectroscopic evidence for distinct conformations of L-3-hydroxyacyl-CoA dehydrogenase;Barycki;J Biol Chem,2000
Cited by 22 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. Crystal structure of multi-functional enzyme FadB from Cupriavidus necator: Non-formation of FadAB complex;Archives of Biochemistry and Biophysics;2022-11
2. Metabolism of phenolics in coffee and plant-based foods by canonical pathways: an assessment of the role of fatty acid β-oxidation to generate biologically-active and -inactive intermediates;Critical Reviews in Food Science and Nutrition;2022-10-13
3. Enzyme active sites: Identification and prediction of function using computational chemistry;Current Opinion in Structural Biology;2022-06
4. Organic Synthesis with Lyases;Enzyme‐Based Organic Synthesis;2022-01-29
5. Substrate specificity and conformational flexibility properties of the Mycobacterium tuberculosis β-oxidation trifunctional enzyme;Journal of Structural Biology;2021-09
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3