Inhibition of tissue factor:factor VIIa-catalyzed factor IX and factor X activation by TFPI and TFPI constructs

Author:

Peraramelli S.1,Thomassen S.1,Heinzmann A.1,Rosing J.1,Hackeng T. M.1,Hartmann R.2,Scheiflinger F.2,Dockal M.2

Affiliation:

1. Department of Biochemistry; Cardiovascular Research Institute Maastricht; University Maastricht; Maastricht the Netherlands

2. Baxter Innovations GmbH; Vienna Austria

Funder

Baxter International

Maastricht University

Publisher

Wiley

Subject

Hematology

Reference48 articles.

1. Activation of factor IX by the reaction product of tissue factor and factor VII: additional pathway for initiating blood coagulation;Osterud;Proc Natl Acad Sci U S A,1977

2. Kinetics of the activation of bovine coagulation factor X by components of the extrinsic pathway. Kinetic behavior of two-chain factor VII in the presence and absence of tissue factor;Silverberg;J Biol Chem,1977

3. Cloning and characterization of a cDNA coding for the lipoprotein-associated coagulation inhibitor shows that it consists of three tandem Kunitz-type inhibitory domains;Wun;J Biol Chem,1988

4. TFPIbeta, a second product from the mouse tissue factor pathway inhibitor (TFPI) gene;Chang;Thromb Haemost,1999

5. Glycosyl phosphatidylinositol anchorage of tissue factor pathway inhibitor;Zhang;Circulation,2003

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