The novel capsazepine analog, CIDD ‐99, significantly inhibits oral squamous cell carcinoma in vivo through a TRPV 1‐independent induction of ER stress, mitochondrial dysfunction, and apoptosis-Reference-Cited by-同舟云学术

The novel capsazepine analog, CIDD ‐99, significantly inhibits oral squamous cell carcinoma in vivo through a TRPV 1‐independent induction of ER stress, mitochondrial dysfunction, and apoptosis

Published:2019-04-04 Issue:5 Volume:48 Page:389-399
ISSN:0904-2512
Container-title:Journal of Oral Pathology & Medicine
language:en
Short-container-title:J Oral Pathol Med

Author:

De La Chapa Jorge J.¹,Singha Prajjal K.²,Self Kristen K.¹,Sallaway McKay L.¹,McHardy Stanton F.³⁴,Hart Matthew J.⁴⁵,McGuff Howard Stan²,Valdez Matthew C.³,Ruiz Francisco³,Polusani Srikanth R.⁵,Gonzales Cara B.¹⁴^ORCID

Affiliation:

1. Department of Comprehensive DentistrySchool of DentistryUT Health San Antonio San Antonio Texas

2. Department of PathologySchool of MedicineUT Health San Antonio San Antonio Texas

3. Center for Innovative Drug DiscoveryDepartment of ChemistryUniversity of Texas at San Antonio San Antonio Texas

4. Mays Cancer CenterUT Health San Antonio San Antonio Texas

5. Center for Innovative Drug Discovery, HTS FacilityDepartment of Biochemistry and Structural BiologyUT Health San Antonio San Antonio Texas

Funder

National Center for Advancing Translational Sciences

National Institutes of Health

National Cancer Institute

Publisher

Wiley

Subject

Periodontics,Cancer Research,Otorhinolaryngology,Oral Surgery,Pathology and Forensic Medicine

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1111/jop.12843

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3. Phase II Multicenter Study of the Antiepidermal Growth Factor Receptor Monoclonal Antibody Cetuximab in Combination With Platinum-Based Chemotherapy in Patients With Platinum-Refractory Metastatic and/or Recurrent Squamous Cell Carcinoma of the Head and Neck

4. Locoregionally recurrent head and neck squamous cell carcinoma: incidence, survival, prognostic factors, and treatment outcomes

5. A Retrospective Analysis of the Outcome of Patients with Recurrent and/or Metastatic Squamous Cell Carcinoma of the Head and Neck Refractory to a Platinum-based Chemotherapy

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4. New Frontiers on ER Stress Modulation: Are TRP Channels the Leading Actors?;International Journal of Molecular Sciences;2022-12-22

5. Inhibition of Ca2+ entry by capsazepine analog CIDD-99 prevents oral squamous carcinoma cell proliferation;Frontiers in Physiology;2022-09-15