Lynch syndrome‐related colorectal carcinomas are <scp>NTRK‐</scp>negative-Reference-Cited by-同舟云学术

Lynch syndrome‐related colorectal carcinomas are NTRK‐negative

Published:2023-05-17 Issue:2 Volume:83 Page:335-336
ISSN:0309-0167
Container-title:Histopathology
language:en
Short-container-title:Histopathology

Author:

Remo Andrea¹,Grillo Federica²^ORCID,Vanoli Alessandro³^ORCID,Parente Paola⁴^ORCID,Mastracci Luca²^ORCID,Angerilli Valentina⁵,Urso Emanuele Damiano⁶,Bergamo Francesca⁷,Fassan Matteo⁵⁸

Affiliation:

1. Department of Pathology “Mater Salutis” Hospital Verona (VR) Italy

2. Department of Surgical and Diagnostic Sciences (DISC) University of Genoa and S. Martino Polyclinic Hospital Genoa (GE) Italy

3. Anatomic Pathology Unit, Department of Molecular Medicine University of Pavia and Fondazione IRCCS San Matteo Hospital Pavia Italy

4. Unit of Pathology, Fondazione IRCCS Ospedale Casa Sollievo della Sofferenza San Giovanni Rotondo, FG Italy

5. Department of Medicine (DIMED), Surgical Pathology Unit University of Padua Padua (PD) Italy

6. Chirurgia Generale 3^, Department of Surgical, Oncological and Gastroenterological Sciences University of Padua Padua Italy

7. Medical Oncology Unit 1, Clinical and Experimental Oncology Department Veneto Institute of Oncology, IOV‐IRCCS Padua (PD) Italy

8. Veneto Institute of Oncology IOV‐IRCCS Padua (PD) Italy

Publisher

Wiley

Subject

General Medicine,Histology,Pathology and Forensic Medicine

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1111/his.14944

Reference6 articles.

1. Current prognostic and predictive biomarkers for gastrointestinal tumors in clinical practice

2. NTRK gene rearrangements are highly enriched in MLH1/PMS2 deficient, BRAF wild-type colorectal carcinomas—a study of 4569 cases

3. NTRK oncogenic fusions are exclusively associated with the serrated neoplasia pathway in the colorectum and begin to occur in sessile serrated lesions

4. NTRK fusion positive colorectal cancer is a unique subset of CRC with high TMB and microsatellite instability

5. Gene fusions and oncogenic mutations in MLH1 deficient and BRAFV600E wild-type colorectal cancers