<scp> <i>NTRK</i> </scp> fusion positive colorectal cancer is a unique subset of <scp>CRC</scp> with high <scp>TMB</scp> and microsatellite instability-Reference-Cited by-同舟云学术

NTRK fusion positive colorectal cancer is a unique subset of CRC with high TMB and microsatellite instability

Published:2022-05-04 Issue:13 Volume:11 Page:2541-2549
ISSN:2045-7634
Container-title:Cancer Medicine
language:en
Short-container-title:Cancer Medicine

Author:

Wang Hui¹,Li Zhi‐Wei²,Ou Qiuxiang³^ORCID,Wu Xue³,Nagasaka Misako⁴^ORCID,Shao Yang³⁵,Ou Sai‐Hong Ignatius⁶^ORCID,Yang Yu⁷

Affiliation:

1. Department of Medical Oncology, Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine Chinese Academy of Medical Sciences Beijing China

2. Department of Internal Medicine Harbin Medical University Cancer Hospital Harbin China

3. Geneseeq Research Institute Nanjing Geneseeq Technology Inc. Nanjing Jiangsu China

4. Karmanos Cancer Institute Wayne State University Detroit Michigan USA

5. School of Public Health Nanjing Medical University Nanjing Jiangsu China

6. Chao Family Comprehensive Cancer Center University of California Irvine School of Medicine Orange California USA

7. Department of Oncology, the Second Affiliated Hospital of Harbin Medical University Harbin Medical University Harbin China

Publisher

Wiley

Subject

Cancer Research,Radiology, Nuclear Medicine and imaging,Oncology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/cam4.4561

Reference24 articles.

1. Trk receptor tyrosine kinases: A bridge between cancer and neural development

2. Molecular characterization of cancers with NTRK gene fusions

3. NTRK fusion-positive cancers and TRK inhibitor therapy

4. Larotrectinib for the treatment of TRK fusion solid tumors

5. Efficacy of Larotrectinib inTRKFusion–Positive Cancers in Adults and Children

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