Epidermal growth factor attenuates tubular necrosis following mercuric chloride damage by regeneration of indigenous, not bone marrow‐derived cells

Author:

Yen Tzung‐Hai123,Alison Malcolm R.24,Goodlad Robert A.2,Otto William R.24,Jeffery Rosemary245,Cook H. Terence6,Wright Nicholas A.24,Poulsom Richard245

Affiliation:

1. Department of Nephrology and Division of Clinical Toxicology Chang Gung Memorial Hospital and College of Medicine Chang Gung University Linkou Taiwan

2. Histopathology Laboratory Cancer Research UK London Research Institute London UK

3. Barts and The London School of Medicine and Dentistry Queen Mary University of London London UK

4. Epithelial Stem Cell Group Centre for Tumour Biology Barts Cancer Institute Barts and The London School of Medicine and Dentistry Queen Mary University of London London UK

5. Molecular Pathology Facility National Centre for Bowel Research and Surgical Innovation Centre for Digestive Diseases Blizard Institute Barts and The London School of Medicine and Dentistry Queen Mary University of London London UK

6. Department of Histopathology Imperial College London UK

Funder

Chang Gung Memorial Hospital

Publisher

Wiley

Subject

Cell Biology,Molecular Medicine

Reference41 articles.

1. Epidermal growth factor enhances renal tubule cell regeneration and repair and accelerates the recovery of renal function in postischemic acute renal failure.

2. Epidermal growth factor accelerates functional recovery from ischaemic acute tubular necrosis in the rat: Role of the epidermal growth factor receptor

3. Epidermal growth factor accelerates renal repair in mercuric chloride nephrotoxicity;Coimbra TM;Am J Physiol,1990

4. Epidermal growth factor accelerates renal tissue repair in a model of gentamicin nephrotoxicity in rats;Morin NJ;Am J Physiol,1992

5. Bone marrow contributes to renal parenchymal turnover and regeneration

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