Proof of pharmacology of Org 48775‐0, a p38 MAP kinase inhibitor, in healthy volunteers-Reference-Cited by-同舟云学术

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Proof of pharmacology of Org 48775‐0, a p38 MAP kinase inhibitor, in healthy volunteers

Published:2020-12-23 Issue:5 Volume:87 Page:2321-2332
ISSN:0306-5251
Container-title:British Journal of Clinical Pharmacology
language:en
Short-container-title:Brit Jnl Clinical Pharma

Author:

Moerland Matthijs¹²,Kales Andrea J.³,Broekhuizen Karen¹^ORCID,Nässander Ulla⁴,Nelissen Rob⁴,Kam Marieke L.¹,Peeters Pierre A.M.⁴⁵,Burggraaf Jacobus¹²⁶

Affiliation:

1. Centre for Human Drug Research Leiden the Netherlands

2. Leiden University Medical Center Leiden The Netherlands

3. Former affiliation Centre for Human Drug Research Leiden the Netherlands

4. Former affiliation Organon/Schering Plough Oss the Netherlands

5. Present affiliation Curare Consulting, Etten‐Leur the Netherlands

6. Leiden Academic Centre for Drug Research Leiden the Netherlands

Funder

Organon BioSciences

Publisher

Wiley

Subject

Pharmacology (medical),Pharmacology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1111/bcp.14655

Reference28 articles.

1. Mitogen activated protein (MAP) kinase signal transduction pathways and novel anti-inflammatory targets

2. Tamayo N. p38 MAP kinase inhibitors: many are made, but few are chosen;Dominguez C;Curr Opin Drug Discov Devel,2005

3. MAPK signalling pathways as molecular targets for anti‐inflammatory therapy—from molecular mechanisms to therapeutic benefits. Biochim Biophys Acta (BBA)‐proteins;Kaminska B;Proteomics,2005

4. Inhibition of p38 MAP kinase as a therapeutic strategy

5. Psoriatic skin lesions induced by tumor necrosis factor antagonist therapy: A literature review and potential mechanisms of action

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