Inhibition of p38 MAP kinase as a therapeutic strategy

Author:

Lee John C,Kumar Sanjay,Griswold Don E,Underwood David C,Votta Bartholomew J,Adams Jerry L

Publisher

Elsevier BV

Subject

Pharmacology

Reference137 articles.

1. Pyrimidinylimidazole inhibitors of CSBP/p38 kinase demonstrating decreased inhibition of hepatic cytochrome P450 enzymes;Adams;Bioorg. Med. Chem. Lett.,1998

2. Pharmacological profile of SB 203580, a selective inhibitor of CSBP/p38 kinase, in animal models of arthritis, bone resorption, endotoxin shock and immune function;Badger;J. Pharmacol. Exp. Ther.,1996

3. SB 203580 inhibits p38 mitogen-activated protein kinase, nitric oxide production, and inducible nitric oxide synthase in bovine cartilage-derived chondrocytes;Badger;J. Immunol.,1998

4. Cdc42 and PAK-mediated signaling leads to Jun kinase and p38 mitogen-activated protein kinase activation;Bagrodia;J. Biol. Chem.,1995

5. Inflammatory mediators of asthma: an update;Barnes;Pharmacol. Rev.,1998

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