Preclinical characterization of 55P0251, a novel compound that amplifies glucose-stimulated insulin secretion and counteracts hyperglycaemia in rodents-Reference-Cited by-同舟云学术

Preclinical characterization of 55P0251, a novel compound that amplifies glucose-stimulated insulin secretion and counteracts hyperglycaemia in rodents

Published:2017-04-03 Issue:8 Volume:19 Page:1088-1096
ISSN:1462-8902
Container-title:Diabetes, Obesity and Metabolism
language:en
Short-container-title:Diabetes Obes Metab

Author:

Stadlbauer Karin¹,Brunmair Barbara¹,Lehner Zsuzsanna¹,Adorjan Immanuel²,Scherer Thomas¹,Luger Anton¹,Bauer Leonhardt²,Fürnsinn Clemens¹^ORCID

Affiliation:

1. Division of Endocrinology & Metabolism, Department of Medicine III; Medical University of Vienna; Vienna Austria

2. 55pharma Drug Discovery & Development AG; Vienna Austria

Funder

Austrian Research Promotion Agency

Publisher

Wiley

Subject

Endocrinology,Endocrinology, Diabetes and Metabolism,Internal Medicine

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1111/dom.12914/fullpdf

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1. Evidence that the multiflorine‐derived substituted quinazolidine 55P0251 augments insulin secretion and lowers blood glucose via antagonism at α 2 ‐adrenoceptors in mice;Diabetes, Obesity and Metabolism;2019-11-07

2. Life Under Hypoxia Lowers Blood Glucose Independently of Effects on Appetite and Body Weight in Mice;Frontiers in Endocrinology;2018-08-28