Evidence that the multiflorine‐derived substituted quinazolidine 55P0251 augments insulin secretion and lowers blood glucose via antagonism at α 2 ‐adrenoceptors in mice

Author:

Lehner Zsuzsanna1,Stadlbauer Karin1,Brunmair Barbara1,Adorjan Immanuel2,Genov Miroslav2,Kautzky‐Willer Alexandra1ORCID,Scherer Thomas1ORCID,Scheinin Mika3,Bauer Leonhardt2,Fürnsinn Clemens1ORCID

Affiliation:

1. Division of Endocrinology and Metabolism, Department of Medicine IIIMedical University of Vienna Vienna Austria

2. 55pharma Drug Discovery and Development AG Vienna Austria

3. Institute of BiomedicineUniversity of Turku Turku Finland

Publisher

Wiley

Subject

Endocrinology,Endocrinology, Diabetes and Metabolism,Internal Medicine

Reference36 articles.

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4. Gurrola‐DíazCM BorelliMI PrzybylAK Garcia‐LopezJS GarzonDL García‐LópezPM.Insulin secretion effect of 2 17‐dioxosparteine 17‐thionosparteine multiflorine and 17‐hydroxy‐lupanine on rat Langerhanʼs islets. In:Lupins for Health and Wealth. Proceedings of the 12th International Lupin Conference Fremantle Western Australia 14‐18 September 2008. International Lupin Association; 2008: 484‐487.

5. Influence of dietary lupin seed mixed diet on serum cholesterol level in normal and diabetic rabbits;Ahmed RT;Egypt J Pharm Sci,1993

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