Affiliation:
1. School of Pharmacy, University of London, Brunswick Square, London, W.C.1
Abstract
Abstract
The viscosities of lysolecithin sols in water were found to be Newtonian at the concentrations investigated. A Couette viscometer was used. In the mixed sols containing both lysolecithin and lecithin, thixotropy was absent at all ratios and only the sol with a high lecithin fraction showed some non-Newtonian behaviour. The axial ratio of the mixed micelles calculated by the Simha method varies with the lecithin/lysolecithin ratio, rising to a maximum when the phospholipid mixture is of one mole lecithin to two moles lysolecithin. This phenomenon is probably due to the packing of the various hydrophobic groups in the micelle.
Publisher
Oxford University Press (OUP)
Subject
Pharmaceutical Science,Pharmacology
Cited by
4 articles.
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