The in Vitro Metabolism of Some Aromatic Polycyclic Hydrocarbon ‘K-Region’ Epoxides and Dihydrodiol Epoxide Derivatives by Rat Liver Preparations
Author:
Affiliation:
1. School of Pharmacy, Portsmouth Polytechnic, Portsmouth, POI 2DZ
Publisher
Oxford University Press (OUP)
Subject
Pharmaceutical Science,Pharmacology
Link
http://academic.oup.com/jpp/article-pdf/33/Supplement_1/89P/37764199/j.2042-7158.1981.tb11748.x.pdf
Reference5 articles.
1. 8,9-Dihydro-8,9-dihydroxybenz(a)anthracene 10,11-oxide: A new type of polycyclic aromatic hydrocarbon metabolite
2. Enzymic Reduction of Aromatic Hydrocarbon Epoxides by the Microsomal Fraction of Rat Liver
3. Reactions of ‘bay-region’ and non-‘bay-region’ diol-epoxides of benz(a)anthracene with DNA: evidence indicating that the major products are hydrocarbon-N2-guanine adducts
4. The formation of “K-region” epoxides as hepatic microsomal metabolites of 7-methylbenz[a]anthracene and 7,12-dimethylbenz[a]anthracene and their 7-hydroxymethyl derivatives
5. Qualitative and quantitative studies on the metabolism of a series of aromatic hydrocarbons by rat-liver preparations
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