The formation of “K-region” epoxides as hepatic microsomal metabolites of 7-methylbenz[a]anthracene and 7,12-dimethylbenz[a]anthracene and their 7-hydroxymethyl derivatives
Author:
Publisher
Elsevier BV
Subject
Pharmacology,Biochemistry
Reference39 articles.
1. METABOLISM OF POLYCYCLIC COMPOUNDS. THE METABOLISM OF 7,12-DIMETHYLBENZ[α]ANTHRACENE BY RAT-LIVER HOMOGENATES
2. Protective Action of Polycyclic Hydrocarbons against Induction of Adrenal Necrosis by Dimethylbenzanthracene
3. Syntheses of Metabolites of 7,12-Dimethylbenz[a]anthracene. 4-Hydroxy-7,12-dimethylbenz[a]anthracene, 7-Hydroxymethyl-12-methylbenz[a]anthracene, Their Methyl Ethers, and Acetoxy Derivatives
4. Induction of Adrenal Damage and Cancer with Metabolites of 7,12-Dimethylbenz(a)Anthracene
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1. Epoxide reductase activity of mammalian liver cytosols and aldehyde oxidase;Carcinogenesis;1994
2. Pathways involved in the metabolism and activation of polycyclic hydrocarbons;Xenobiotica;1986-01
3. In vitro activation of the promutagens 2-acetamidofluorene, cyclophosphamide and 7,12-dimethylbenzanthracene by constitutive ferret and rat hepatic S-9 fractions;Toxicology;1984-05
4. The in Vitro Metabolism of Some Aromatic Polycyclic Hydrocarbon ‘K-Region’ Epoxides and Dihydrodiol Epoxide Derivatives by Rat Liver Preparations;Journal of Pharmacy and Pharmacology;1981-12
5. Identification of novel 7,12-dimethylbenz[a]anthracene adducts in cellular RNA;Biochemistry;1981-07-21
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