Affiliation:
1. Department of Pharmacology, School of Medicine, University of Auckland, Private Bag, Auckland, New Zealand
Abstract
Abstract
The KCl contracted rat aorta is relaxed by procaterol, (±)-,(+)-and (—)-pindolol. The relaxations to procaterol, but not to (±)-pindolol, were prevented by ICI 118,551 at 10−6 M. The relaxations to (±)-pindolol are, therefore, not due to β-adrenoceptor agonism. At 10−7 M ICI 118,551, (±)-, (+)-and (-)-pindolol were β2-adrenoceptor antagonists as they inhibited the relaxant responses of the aorta to procaterol.
Publisher
Oxford University Press (OUP)
Subject
Pharmaceutical Science,Pharmacology
Cited by
10 articles.
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