The sorption of isosorbide-5-mononitrate to intravenous delivery systems-Reference-Cited by-同舟云学术

The sorption of isosorbide-5-mononitrate to intravenous delivery systems

Published:1990-06 Issue:6 Volume:42 Page:433-434
ISSN:2042-7158
Container-title:Journal of Pharmacy and Pharmacology
language:en
Short-container-title:

Author:

De Muynck C¹,Colardyn F²,Remon J P¹

Affiliation:

1. Laboratory of Pharmaceutical Technology, State University of Gent, Harelbekestraat 72, B-9000 Gent

2. Intensive Care Department, University Hospital, De Pintelaan 185, B-Gent, Belgium

Abstract

Abstract The sorption of isosorbide-5-mononitrate, diluted in 0.9% NaCl or 10% glucose solutions, to intravenous delivery systems was investigated. Infusion bags, burettes, a syringe, infusion tubings and end-line filters were tested in static and in dynamic experiments. No clinically significant sorption was detected during those experiments. The use of PVC tubings of different hardness did not influence the results.

Publisher

Oxford University Press (OUP)

Subject

Pharmaceutical Science,Pharmacology

Link

http://academic.oup.com/jpp/article-pdf/42/6/433/37237999/j.2042-7158.1990.tb06585.x.pdf

Reference9 articles.

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2. The sorption of isosorbide dinitrate to intravenous delivery systems;De Muynck;J. Pharm. Pharmacol.,1988

3. The sorption of nitroglycerin by infusion sets;De Rudder;Ibid.,1987

4. Validation of high performance liquid chromatographic methods for analysis of sustained release preparations containing nitroglycerin, isosorbide dinitrate, or pentaerythritol tetranitrate;Gelber;J. Pharm. Sci.,1983

5. Der Einfluss von metaboliten des Isosorbiddinitrates auf das Belastungs-Electrokardiagramm bei Koronarinsuffizienz;Michel;Herz/Kreislauf,1976

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